Cardiac MRI in Small Animals.
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Abstract | :
Cardiac magnetic resonance (MR) imaging of mice is a valuable tool for the precise in vivo diagnosis and prognosis of heart defects. This detailed protocol describes the method of cardiac MR imaging in mice step by step. A series of MR images captures the contractile function of the mouse heart and post-processing of the image data yields morphometric parameters (myocardial mass, myocardial wall thickness, ventricular end-systolic and end-diastolic volume) as well as functional parameters (stroke volume and ejection fraction). This protocol may also serve as a starting point for MR imaging of rats, by using larger image dimensions (field-of-view) and MR hardware suitable for larger animals. |
Year of Publication | :
0
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Journal | :
Methods in molecular biology (Clifton, N.J.)
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Volume | :
1718
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Number of Pages | :
269-284
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Date Published | :
2018
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ISSN Number | :
1064-3745
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URL | :
https://dx.doi.org/10.1007/978-1-4939-7531-0_16
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DOI | :
10.1007/978-1-4939-7531-0_16
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Short Title | :
Methods Mol Biol
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