Cognitive and somatiform changes occur with ageing and are often attributed to late-onset hypogonadism. Testosterone replacement in older men remains controversial despite increasing evidence of symptomatic and clinical benefit in relation to improvements in sexual dysfunction, muscle mass, and diabetic control. The controversial areas related to cardiovascular safety and risk of prostate cancer need to be considered.

European urology focus

http://linkinghub.elsevier.com/retrieve/pii/S2405-4569(17)30273-0

Eur Urol Focus